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國(guó)家衛(wèi)健委功能性腦疾病診治重點(diǎn)實(shí)驗(yàn)室

研究方向(含承擔(dān)課題)

以高通量組學(xué)大數(shù)據(jù)輔助的系統(tǒng)生物學(xué)手段,探索抑郁癥的分子變化規(guī)律,為疾病的機(jī)制解析和臨床診療提供新的理論依據(jù)。重慶市委組織部,重慶英才·青年拔尖人才獲得者。

著作論文

1. Liu Y; Wang H; Gui S; Zeng B; Pu J; Zeng L; Luo Y; Zhou C; Song J; Ji P; Wei H; Xie P ; Proteomics analysis of the gut-brain axis in a gut microbiota-dysbiosis model of depression, Translational Psychiatry, 2021, 11(1): 568.

2. Liu Y; Song X; Liu X; Pu J; Gui S; Xu S; Tian L; Zhong X; Zhao L; Wang H; Liu L; Xu G; Xie P ; Alteration of lipids and amino acids in plasma distinguish schizophrenia patients from controls: A targeted metabolomics study, Psychiatry and Clinical Neurosciences, 2021, 75(4): 138-144.

3. Pu J; Liu Y; Gui S; Tian L; Yu Y; Song X; Zhon, X; Chen, X; Chen W; Zheng P; Zhang H; Gong X; Liu L; Wu J; Wang H; Xie P; Metabolomic changes in animal models of depression: a systematic analysis, Molecular Psychiatry, 2021, 26(12): 7328-7336.

4.Pu J; Yu Y; LiuY; Tian L; Gui S; Zhong X; Fan C; Xu S; Song X; Liu L; Yang L; Zheng P; Chen J; Cheng K; Zhou C; Wang H; Xie P; MENDA: a comprehensive curated resource of metabolic characterization in depression, Briefings in Bioinformatics, 2020, 21(4): 1455-1464.

5. Liu Y; Zhou X; Yang L; Wang H; Zhang Y; Pu J; Liu L; Gui S; Zeng L; Chen J; Zhou C; Xie P; Social defeat stress causes depression-like behavior with metabolite changes in the prefrontal cortex of rats, PLos One, 2017, 12(4): e0176725.

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