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國家衛(wèi)健委功能性腦疾病診治重點實驗室

研究方向(含承擔課題)

腸道微生物的抑郁癥機制研究。獲得年2023 重慶市中青年醫(yī)學高端人才稱號。

著作論文

1. Liu L#, Wang H#, Zhang H#, Chen X, Zhang Y, Wu J, Zhao L, Wang D, Pu J, Ji P, Xie P. Toward a Deeper Understanding of Gut Microbiome in Depression: The Promise of Clinical Applicability.Adv Sci (Weinh). 2022;9(35):e2203707. (IF: 17.521)

2. Liu L#, Wang H#, Rao X#, Yu Y, Zheng P, Zeng B, Zhao Libo, Zhou C, Pu J, Yang Deyu, Fang Liang, Wei H, Xie P. Comprehensive analysis of the lysine acetylome and succinylome in the hippocampus of gut microbiota dysbiosis mice. J Adv Res, 2021;30:27-38. (IF: 12.822)

3. Liu L#, Wang H#, Chen X, Zhang Y, Zhang H, Xie P. Gut microbiota and its metabolites in depression: from pathogenesis to treatment. EbioMedicine. 2023. Accept (IF: 11.205)

4. Zhou X#, Liu L#, Lan X#, Cohen D, Zhang Y, Ravindran AV, Yuan S, Zheng P, Coghill D, Yang L, Hetrick SE, Jiang X, Benoliel JJ, Cipriani A, Xie P. Polyunsaturated fatty acids metabolism, purine metabolism and inosine as potential independent diagnostic biomarkers for major depressive disorder in children and adolescents. Mol Psychiatry, 2019, 24(10):1478-1488. (IF: 15.992)

5. Liu L, Wang H, Chen X, Zhang Y, Li W, Rao X, Liu Y, Zhao L, Pu J, Gui S, Yang D, Fang L, Xie P. Integrative Analysis of Long Non-coding RNAs, Messenger RNAs, and MicroRNAs Indicates the Neurodevelopmental Dysfunction in the Hippocampus of Gut Microbiota-Dysbiosis Mice. Front Mol Neurosci. 2022;14:745437. (IF: 6.261)

6. Yu Y#, Wang H#, Rao X#Liu L#, Zheng P, Li W, Zhou W, Chai T, Ji P, Song J, Wei H, Xie P. Proteomic Profiling of Lysine Acetylation Indicates Mitochondrial Dysfunction in the Hippocampus of Gut Microbiota-Absent Mice. Front Mol Neurosci. 2021;14:594332. (IF: 6.261)

7. Liu L, Wang H, Chen X, Xie P. Gut microbiota: a new insight into neurological diseases. Chin Med J (Engl). 2022 Jul 14. doi: 10.1097/CM9.0000000000002212. (IF: 6.151)

8. Liu L#, Zhou X#, Zhang Y, Pu J, Yang L, Yuan S, Zhao L, Zhou C, Zhang H, Xie P. Hippocampal metabolic differences implicate distinctions between physical and psychological stress in four rat models of depression. Transl Psychiatry, 2018;8(1):4. (IF: 5.182)

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