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 首頁(yè)  國(guó)家衛(wèi)健委功能性腦疾病診治重點(diǎn)實(shí)驗(yàn)室  人員隊(duì)伍  研究人員 詳細(xì)

國(guó)家衛(wèi)健委功能性腦疾病診治重點(diǎn)實(shí)驗(yàn)室

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桂思雯

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研究方向(含承擔(dān)課題) 著作論文

導(dǎo)航菜單

研究方向(含承擔(dān)課題)

利用計(jì)算生物學(xué)和生物信息學(xué)的手段發(fā)現(xiàn)和解析抑郁癥的發(fā)生發(fā)展過(guò)程中基因組、轉(zhuǎn)錄組、蛋白組和代謝組等多維度分子變化規(guī)律，幫助抑郁癥致病機(jī)制的深入理解和新的診斷方法的開發(fā)。

著作論文

1. Siwen Gui#; Yiyun Liu; Juncai Pu; Xuemian Song; Xiaopeng Chen; Weiyi Chen; Xiaogang Zhong;Haiyang Wang; Lanxiang Liu; Peng Xie ; Comparative analysis of hippocampal transcriptional features between major depressive disorder patients and animal models, Journal of Affective Disorders, 2021, Oct 1(293): 19-28.

2. Juncai Pu; Yiyun Liu; Siwen Gui#; Lu Tian; Yue Yu; Xuemian Song; Xiaogang Zhong; Xiaopeng; Chen; Weiyi Chen; Peng Zheng; Hanping Zhang; Xue Gong; Lanxiang Liu; Jing Wu; Haiyang Wang; Peng Xie ; Metabolomic changes in animal models of depression: a systematic analysis, Molecular Psychiatry, 2021, Dec 26(12): 7328-7336.

3. Yiyun Liu; Haiyang Wang; Siwen Gui#; Benhua Zeng; Juncai Pu; Peng Zheng; Li Zeng; Yuanyuan; Luo; You Wu; Chanjuan Zhou; Jinlin Song; Ping Ji; Hong Wei; Peng Xie ; Proteomics analysis of the gut-brain axis in a gut microbiota-dysbiosis model of depression, Translational Psychiatry, 2021, 11(1): 0-568.

4. Xuemian Song; Yiyun Li; Juncai P; Siwen Gui#; Xiaogang Zhong; Xiaopeng Che; Weiyi Che; Xiang Chen; Yue Chen; Haiyang Wang; Ke Chen; Libo Zhao; Peng Xie. Transcriptomics Analysis Reveals Shared Pathways in Peripheral Blood Mononuclear Cells and Brain Tissues of Patients With Schizophrenia. Frontiers in Psychiatry. 2021 Sep 22;12:716722.

5. Siwen Gui#; Yiyun Liu; Xiaogang Zhong; Xinyu Liu; Peng Zheng; Juncai Pu; Jian Zhou;Jianjun Chen; Libo Zhao; Lanxiang Liu; Guowang Xu; Peng Xie ; Plasma disturbance of phospholipid metabolism in major depressive disorder by integration of proteomics and metabolomics, Neuropsychiatric Disease and Treatment, 2018, June 6(14): 1451-1461.