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 首頁  國家衛(wèi)健委功能性腦疾病診治重點(diǎn)實(shí)驗(yàn)室  人員隊伍  博士后 詳細(xì)

國家衛(wèi)健委功能性腦疾病診治重點(diǎn)實(shí)驗(yàn)室

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研究方向(含承擔(dān)課題) 著作論文

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研究方向(含承擔(dān)課題)

重慶醫(yī)科大學(xué)附屬第一醫(yī)院神經(jīng)內(nèi)科醫(yī)師，圍繞腦血管疾病，聚焦腦卒中神經(jīng)影像和功能預(yù)后，開展了一系列研究。共發(fā)表42篇科研論文，其中SCI論文36篇。以第一作者（含共同）發(fā)表SCI論文11篇，CSCD期刊收錄1篇。主持國家博士后面上資助、重慶市自然科學(xué)基金面上項目、重慶市科衛(wèi)聯(lián)合青年項目各1項。獲得重慶市科技進(jìn)步獎二等獎。任重慶卒中學(xué)會神經(jīng)重癥分會委員、重慶卒中學(xué)會腦出血專委會委員。作為課題組骨干參與國家重點(diǎn)研發(fā)項目、國家自然科學(xué)基金面上項目、重慶市科衛(wèi)聯(lián)合醫(yī)學(xué)科研項目、重慶市杰出青年科學(xué)基金項目、“成渝地區(qū)雙城經(jīng)濟(jì)圈建設(shè)”科技創(chuàng)新項目。1項成果被F1000推薦為臨床醫(yī)學(xué)必讀論文。1項成果被中國科學(xué)技術(shù)信息研究所評為中國精品科技期刊頂尖學(xué)術(shù)論文（F5000）。多項成果并被寫入2項中國指南、1項美國指南（2022版）和1項國際標(biāo)準(zhǔn)，獲得國家專利（專利號: ZL 202110689924.7）1項。Transl Stroke Res、J Neurochem、Molecular Neurobiology、BMC Neurol（IF=2.6）等雜志審稿人。

著作論文

1. Yang WS, Zhang SQ, Shen YQ, Wei X, Zhao LB, Xie XF, Deng L, Li XH, Lv XN, Lv FJ, Dowlatshahi D, Li Q*, Xie P^*. Noncontrast Computed Tomography Makers as Predictors of Revised Hematoma Expansion in Acute Intracerebral Hemorrhage. J Am Heart Assoc. 2021 Feb 2;10(3):e018248.

2. Shen YQ^#, Yang WS^#, Xiong X, Li XH, Xiao ZS, Yu JL, Liu FY, Gui SW, Xie XF, Lv FJ, Zhao LB, Hu LB, Manaenko A,Xie P*, Li Q^*. Integrated Multi-Omics Analysis Identifies a Novel Biomarker Associated With Prognosis in Intracerebral Hemorrhage. Oxid Med Cell Longev. 2021. Dec 14.

3. Yang WS, Shen YQ, Wei X, Zhao LB, Liu QJ, Xie XF, Zhang ZW, Deng L, Lv XN, Zhang SQ, Li XH, Li Q^*, Xie P^*. New Prediction Models of Functional Outcome in Acute Intracerebral Hemorrhage: The dICH Score and uICH Score [J]. Front Neurol. 2021 May 5;12:655800.

4. Yang WS, Shen YQ, Zhang XD, Zhao LB, Wei X, Xiong X, Xie XF, Li R, Deng L, Li XH, Lv XN, Lv FJ, Li Q^*, Xie P^*. Hydrocephalus Growth: Definition, Prevalence, Association with Poor Outcome in Acute Intracerebral Hemorrhage. Neurocrit Care. 2021 Aug;35(1):62-71.

5. Yang WS, Shen YQ, Yang X, Li XH, Xu SH, Zhao LB, Li R, Xiong X, Bai SJ, Wu QY, Manaenko A, Li Q*, Xie P*. MicroRNA transcriptomics analysis identifies dysregulated hedgehog signaling pathway in a mouse model of acute intracerebral hemorrhage exposed to hyperglycemia. J Stroke Cerebrovasc Dis. 2022 Jan 10;31(3):106281.

6. Yang WS, Liu JY, Shen YQ, Xie XF, Zhang SQ, Liu FY, Yu JL, Ma YB, Xiao ZS, Duan HW, Li Q, Chen SX, Xie P. Quantitative Imaging for Predicting Hematoma Expansion in Intracerebral Hemorrhage: A Multimodel Comparison. J Stroke Cerebrovasc Dis. 2024 Apr 22:107731.

7. Yang WS, Li Q, Li R, Liu QJ, Wang XC, Zhao LB, Xie P. Defining the Optimal Midline Shift Threshold to Predict Poor Outcome in Patients with Supratentorial Spontaneous Intracerebral Hemorrhage. Neurocrit Care. 2018 Jun;28(3):314-321.

8. Yang WS, Li R, Shen YQ, Wang XC, Liu QJ, Wang HY, Li Q, Yao GE, Xie P^*. Importance of lipid ratios for predicting intracranial atherosclerotic stenosis. Lipids Health Dis. 2020 Jul 4;19(1):160. Li Q^#, Yang WS^#, Wang XC^#, Cao D, Zhu D, Lv FJ, Liu Y, Yuan L, Zhang G, Xiong X, Li R, Hu YX, Qin XY, Xie P^*. Blend sign predicts poor outcome in patients with intracerebral hemorrhage. PLoS One. 2017, 12(8): e0183082.

9. Luo S^#, Yang WS^#, Shen YQ, Chen P, Zhang SQ, Jia Z, Li Q, Zhao JT, Xie P. The clinical value of neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and D-dimer-to-fibrinogen ratio for predicting pneumonia and poor outcomes in patients with acute intracerebral hemorrhage. Front Immunol. 2022 Oct 10;13:1037255.

10. Li XH^#, Yang WS^#, Shen YQ, et al. Analysis of Age-Dependent Transcriptomic Changes in Response to Intracerebral Hemorrhage in Mice. Front Mol Neurosci. 2022 May 23;15:908683.