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國家衛(wèi)健委功能性腦疾病診治重點(diǎn)實(shí)驗(yàn)室

研究方向(含承擔(dān)課題)

主要從事抑郁癥腸-腦軸分子機(jī)制研究，第一作者（含共同）在Nature Neuroscience（IF=25.0）、Molecular Psychiatry（IF=11.0）等雜志發(fā)表SCI論文4篇。作為課題組骨干成員，參與發(fā)表SCI論文6篇（其中IF>10，4篇），參與2項(xiàng)國家自然科學(xué)基金面上項(xiàng)目。

著作論文

1. Wu J#, Li Y#, Huang Y#, Liu L, Zhang H, Nagy C, Tan X, Cheng K, Liu Y, Pu J, Wang H, Perry SW, Turecki G, Wong ML, Licinio J, Zheng P*, Xie P*. Integrating spatial and single-nucleus transcriptomic data elucidates microglial-specific responses in female cynomolgus macaques with depressive-like behaviors. Nat Neurosci. 2023 Aug;26(8):1352-1364. doi: 10.1038/s41593-023-01379-4. IF=28.8

2. Huang Y#, Wu J#, Zhang H#, Li Y, Wen L, Tan X, Cheng K, Liu Y, Pu J, Liu L, Wang H, Li W, Perry SW, Wong ML, Licinio J, Zheng P*, Xie P*. The gut microbiome modulates the transformation of microglial subtypes. Mol Psychiatry. 2023 Apr;28(4):1611-1621. doi.org/10.1038/s41380-023-02017-y. IF=13.4

3. Tan X#, Huang Y#, Chai T, Zhao X, Li Y, Wu J, Zhang H, Duan J, Liang W, Yin B, Cheng K, Yu G, Zheng P, Xie P. Differential Gut Microbiota and Fecal Metabolites Related With the Clinical Subtypes of Myasthenia Gravis. Front Microbiol. 2020 Sep 8;11:564579. doi: 10.3389/fmicb.2020.564579. IF=4.2

4. Liang W#, Huang Y#, Tan X#, Wu J, Duan J, Zhang H, Yin B, Li Y, Zheng P, Wei H, Xie P. Alterations Of Glycerophospholipid And Fatty Acyl Metabolism In Multiple Brain Regions Of Schizophrenia Microbiota Recipient Mice. Neuropsychiatr Dis Treat. 2019 Nov 19;15:3219-3229. doi: 10.2147/NDT.S225982. IF=2.1

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