圍繞抑郁癥臨床診療及發(fā)病機制開展系列研究，以大數(shù)據(jù)輔助的循證醫(yī)學(xué)和深度機器學(xué)習(xí)為手段，構(gòu)建抑郁癥分層化、個體化的治療體系；結(jié)合現(xiàn)代分子生物學(xué)技術(shù)，探索抑郁癥的分子變化規(guī)律，為疾病的機制解析和臨床診療提供新的理論依據(jù)。

以第一和通訊作者在Evidence-based mental health（IF=13.54），International Journal of Mental Health and Addiction（IF=8.0），General Hospital Psychiatry（IF=7.59），BMC psychiatry（IF=5.738）等雜志發(fā)表SCI論文6篇；其它作者參與發(fā)表SCI論文13篇，總計IF=159分，單篇最高77.06。主持中國博士后科學(xué)基金面上資助，重慶市自然科學(xué)基金面上資助，重慶市博士后研究項目特別資助，重慶市2023一流學(xué)科建設(shè)（博士后培育項目）等課題。參研科技創(chuàng)新2030“腦科學(xué)與類腦研究”（青年科學(xué)家項目，500萬元），重慶市自然科學(xué)基金（杰出青年項目，50萬元）。申請國家發(fā)明專利1項，擔任European heart journal（IF=39.30）、BMC Psychiatry（IF=5.74）、Frontiers in Genetics（IF=4.77）等雜志審稿人。

1. Xiang Y#, Cipriani A, Teng T, Del Giovane C, Zhang Y, Weisz JR, Li X, Cuijpers P, Liu X, Barth J, Jiang Y, Cohen D, Fan L, Gillies D, Du K, Ravindran AV, Zhou X*, Xie P*. Comparative efficacy and acceptability of psychotherapies for post-traumatic stress disorder in children and adolescents: a systematic review and network meta-analysis. Evid Based Ment Health. 2021 Nov;24(4):153-160.(IF=13.54)

2. Xiang Y#, Wang L,# Gu P,# Wang C,# Tian Y,# Shi W,# Deng F,# Zhang Y,# Gao L,# Wang K, Wang Y, He J, Zhao W, Bi X, Hu J, Zhong L, Guo Y, Zhou X, Wang H,* Xie P,* A Randomized, Double-Blind, Positive-Controlled, Multicenter Clinical Trial on the Efficacy and Safety of ShuganJieyu Capsule and St. John’s Wort for Major Depressive Disorder with Somatic Complaints. Int J Ment Health Addiction (2023). https://doi.org/10.1007/s11469-023-01222-8（IF=8.0）

3. Xie S#, Cheng Q#, Tan S, Li H, Huang T, Xiang Y*, Zhou X*. The efficacy and acceptability of group trauma-focused cognitive behavior therapy for the treatment of post-traumatic stress disorder in children and adolescents: A systematic review and meta-analysis. General hospital psychiatry, 86, 127-134.（IF=7.59）

4. Xiang Y#, Cuijpers P#, Teng T, Li X, Fan L, Liu X, Jiang Y, Du K, Lin J, Zhou X*, Xie P*. Comparative short-term efficacy and acceptability of a combination of pharmacotherapy and psychotherapy for depressive disorder in children and adolescents: a systematic review and meta-analysis. BMC Psychiatry. 2022 Feb 22;22(1):139.(IF=5.74)

5. Huang T#, Li H#, Tan S, Xie S, Cheng Q, Xiang Y*, Zhou X*. The efficacy and acceptability of exposure therapy for the treatment of post-traumatic stress disorder in children and adolescents: a systematic review and meta-analysis. BMC Psychiatry. 2022 Apr 12;22(1):259.(IF=5.74)